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                  • EI
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                  • 食品科學與工程領域高質量科技期刊分級目錄第一方陣T1
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                  • 北大核心期刊
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                  • 中國科技核心期刊CSTPCD
                  • 中國生物醫學SinoMed
                  中國精品科技期刊2020
                  蒲蓮蓮,楊穎,劉漫,等. 養生代餐粉的熟化工藝篩選與抗抑郁功能評價[J]. 食品工業科技,2023,44(21):386?394. doi: 10.13386/j.issn1002-0306.2023010001.
                  引用本文: 蒲蓮蓮,楊穎,劉漫,等. 養生代餐粉的熟化工藝篩選與抗抑郁功能評價[J]. 食品工業科技,2023,44(21):386?394. doi: 10.13386/j.issn1002-0306.2023010001.
                  PU Lianlian, YANG Ying, LIU Man, et al. Curing Process Screening and Antidepression Functional Evaluation of Health Meal Replacement Powder[J]. Science and Technology of Food Industry, 2023, 44(21): 386?394. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2023010001.
                  Citation: PU Lianlian, YANG Ying, LIU Man, et al. Curing Process Screening and Antidepression Functional Evaluation of Health Meal Replacement Powder[J]. Science and Technology of Food Industry, 2023, 44(21): 386?394. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2023010001.

                  養生代餐粉的熟化工藝篩選與抗抑郁功能評價

                  Curing Process Screening and Antidepression Functional Evaluation of Health Meal Replacement Powder

                  • 摘要: 目的:研究養生代餐粉的熟化工藝并對其抗抑郁功能進行評價。方法:以蒸煮、炒制、微波等方法對代餐粉的中藥混合粉進行熟化,測定其理化指標、總多糖、總黃酮及體外消化特性;采用腹腔注射LPS造小鼠抑郁模型,隨機分為空白組、模型組、鹽酸氟西汀組及養生代餐粉組,通過懸尾及強迫游泳實驗觀察代餐粉對小鼠行為學的影響,并測定代餐粉對小鼠血清IL-1β、TNF-α、5-HT、NE及腦組織BDNF含量的影響。結果:經熟化處理后,最優熟化工藝擠壓膨化組的水溶性指數(WSI)、吸水性指數(WAI)、離心沉淀率(SR)、分散時間、潤濕時間、總多糖含量、總黃酮含量分別為34.35%、3.18 g/g、52.16%、184.12 s、195.02 s、32.2 mg/g、0.62 mg/g。表明擠壓膨化對中藥粉沖調性改善不如烘烤等其他熟化工藝,但可明顯提高中藥粉末可溶性小分子物質的含量,并顯著增加活性物質含量。體外消化結果表明,擠壓膨化對中藥粉總黃酮釋放量稍有影響,但其快消化淀粉RDS含量(63.52%)較低,慢消化淀粉SDS含量(34.14%)顯著高于其他各組(P<0.05)。動物實驗結果顯示,與模型組比,代餐粉可明顯降低小鼠懸尾及強迫游泳不動時間,下調小鼠血清IL-1β、TNF-α水平,增加5-HT、NE及腦組織BDNF含量(P<0.01)。結論:擠壓膨化工藝理化指標符合產品營養吸收性好的要求,功能性成分增加較大,升糖指數低、健康養生。因此,擠壓膨化是養生代餐粉的最佳制備工藝。養生代餐粉可明顯改善抑郁模型小鼠的抑郁樣行為及指標。

                     

                    Abstract: Objective: To study the curing process of health meal replacement powder (HMR) and evaluate its anti-depression function. Methods: The mixed traditional Chinese medicine powder of HMR was cured by stewing, stir-frying, microwave and other processes. Meanwhile, the physicochemical indexes, total polysaccharides, total flavonoids and characteristics in vitro digestive were determined. The depression model mice were established by intraperitoneal injection of LPS, and mice were randomly divided into blank control group, model control group, fluoxetine hydrochloride group and HMR group. Using the tail suspension test and forced swimming test in mice, the antidepressant effect of HMR was observed. The behavior, IL-1β, TNF-α, 5-HT, NE and BDNF of mice were determined. Results: After curing, the water solubility index (WSI), water absorption index (WAI), centrifugal sediment rate (SR), dispersibility time, wettability time, total polysaccharide and total flavonoids content of extrusion group were 34.35%, 3.18 g/g, 52.16%, 184.12 s, 195.02 s, 32.2 mg/g and 0.62 mg/g. The results showed that extrusion could not improve the soakage and disperal of Chinese medicine powder as much as other curing processes like baking, but it could significantly increase the content of soluble small molecules and active substances of Chinese medicine powder. Results of in vitro digestion showed that extrusion had a little effect on the release of total flavonoids from Chinese medicine powder, but the content of rapidly digestible starch (RDS) (63.52%) was lower, and the content of slowly digestible starch (SDS) (34.14%) was significantly higher than that of other groups (P<0.05). The results of animal experiments showed that compared with the model control group, HMR group could significantly reduce the resting time of tail suspension and swimming, down-regulate the levels of IL-1β and TNF-α, up-regulate the levels of 5-HT and NE, and increase the contents of BDNF (P<0.01). Conclusion: The physicochemical indexes of extrusion process sample meet the good nutrient absorbability requirements of products, and its functional components increase greatly, the extrusion sample was slow GI and health regimen. Therefore, extrusion is the best curing process to prepare HMR. HMR can significantly improve the depression-like behavior and indexes of depressive model mice.

                     

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